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陈少鹏

作者:    新闻来源:    发布时间:2011-08-18

   陈少鹏:研究方向包括生物大分子人工进化及辐射生物学。

科研项目:

1.主持国家自然科学基金“胞间信号介导的近旁干涉效应及其机理”,项目编号:30970680

研究论文:

1.Chen S, Qiu J, Chen C, Liu C, Liu Y, An L, Jia J, Tang J, Wu L, Hang H. Affinity maturation of anti-TNF-α scFv with somatic hypermutation in non-B cells, Plosone, revised.

2.Chen S, Zhao Y, Han W, Chiu SK, Zhu L, Wu L, Yu KN. Rescue effects in radiobiology: unirradiated bystander cells assist irradiated cells through intercellular signal feedback. Mutat Res. 2011 Jan 10;706(1-2):59-64. Epub 2010 Nov 10.

3.Zhao G, Chen S, Wang L, Zhao Y, Wang J, Wang X, Zhang W, Wu R, Wu L, Wu Y, Xu A. Cellular ATP content was decreased by a homogeneous 8.5?T static magnetic field exposure: Role of reactive oxygen species. Bioelectromagnetics. 2011 Feb;32(2):94-101.

4.Han W, Chen S, Yu KN, Wu L.Nitric oxide mediated DNA double strand breaks induced in proliferating bystander cells after alpha-particle irradiation. Mutat Res. 2010 Feb 3;684(1-2):81-9.

5.Han W, Wu L, Chen S, Yu KN.Exogenous carbon monoxide protects the bystander Chinese hamster ovary cells in mixed coculture system after alpha-particle irradiation. Carcinogenesis. 2010 Feb;31(2):275-80. Epub 2009 Nov 27.

6.Yang G, Wu L, Chen S, Zhu L, Huang P, Tong L, Zhao Y, Zhao G, Wang J, Mei T, Xu A, Wang Y., Mitochondrial dysfunction resulting from loss of cytochrome c impairs radiation-induced bystander effect. Br J Cancer. 2009 Jun 16;100(12):1912-6. Epub 2009 May 19.

7.Chen S, Zhao Y, Zhao G, Han W, Bao L, Yu KN, Wu L. Up-regulation of ROS by mitochondria-dependent bystander signaling contributes to genotoxicity of bystander effects. Mutat Res. 2009 Jun 18;666(1-2):68-73. Epub 2009 Apr 23.

8.Zhu L, Han W, Chen S, Zhao Y, Jiang E, Bao L, Pei B, Yang G, Zhao G, Wang J, Xu A, Wu L. Radiation-induced bystander effects enhanced by elevated sodium chloride through sensitizing cells to bystander factors. Mutat Res. 2008 Sep 26;644(1-2):43-7. Epub 2008 Jul 3.

9.Chen S, Zhao Y, Han W, Zhao G, Zhu L, Wang J, Bao L, Jiang E, Xu A, Hei TK, Yu Z, Wu L. Mitochondria-dependent signalling pathway are involved in the early process of radiation-induced bystander effects. Br J Cancer. 2008 Jun 3;98(11):1839-44. Epub 2008 May 13.